Keywords
Tympanometry
Otitis media with effusion
Eustachian tube dysfunction
Palatoplasty
Pediatric otolaryngology
Abstract
This study investigates the prevalence of middle ear dysfunction in children with cleft palate compared to a non-cleft control group. A cross-sectional analysis was conducted involving 45 children with cleft palate and 45 age-matched controls without cleft palate. Tympanometric assessments were performed to evaluate middle ear function. The findings revealed a significantly higher prevalence of middle ear dysfunction in the cleft palate group (73.3%) compared to the control group (26.7%). Type B tympanograms, indicative of middle ear effusion, were predominant in the cleft palate group (64.4%). The prevalence of middle ear dysfunction 3 months pre and post-operatively was 63.8%, thus cleft participant did not show any remarkable improvement in their middle ear function 3 months after palatoplasty [p value =1.0]. The study underscores the importance of regular otologic evaluations and timely interventions to prevent hearing loss and support speech and language development in children with cleft palate.
References
Adeyemo, W. L., James, O., Butali, A., & Ogunlewe, M. O. (2009). Cleft lip and palate: Prevalence and clinical features in a Nigerian hospital. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 35(2), 71–75.
Bluestone, C. D. (2004). Eustachian tube function and dysfunction. In Pediatric Otolaryngology (pp. 463-485). Philadelphia, PA: Saunders.
Bluestone, C. D. (2004). Studies in otitis media: Children's Hospital of Pittsburgh-University of Pittsburgh Progress Report—2004. The Laryngoscope, 114, 1–26.
Bluestone, C.D. & Klein, J.O. (2007). Otitis Media in Infants and Children. 4th ed. Hamilton, Ontario: BC Decker.
Broen, P.A., Devers, M.C., Doyle, S.S., Prouty, J.M. & Moller, K.T. (1996). Acquisition of linguistic and phonological skills in children with cleft palate. Cleft Palate-Craniofacial Journal, 33(5), pp. 429–435.
Flynn, T., Möller, C., Jönsson, R. & Lohmander, A. (2009). The high prevalence of otitis media with effusion in children with cleft palate as compared to children without clefts. International Journal of Pediatric Otorhinolaryngology, 73(10), pp. 1441–1446.
Flynn, T., Möller, C., Jönsson, R., & Lohmander, A. (2009). A longitudinal study of hearing and middle ear status in individuals with cleft lip and palate. The Cleft Palate-Craniofacial Journal, 46(5), 512–518.
Flynn, T., Möller, C., Jönsson, R., & Lohmander, A. (2009). The high prevalence of otitis media with effusion in children with cleft lip and palate as compared to children without clefts. International Journal of Pediatric Otorhinolaryngology, 73(10), 1441-1446. https://doi.org/10.1016/j.ijporl.2009.07.015
Funamura, J. L., Lee, J. W., McKinney, S., Bayoumi, A. G., Senders, C. W., & Tollefson, T. T. (2019). Children with cleft palate: Predictors of otologic issues in the first 10 years. Otolaryngology–Head and Neck Surgery, 160(5), 902-910. https://doi.org/10.1177/0194599818821902
Handzić-Cuk, J., Cuk, V., Gluhinić, M., Risavi, R., & Stajner-Katusić, S. (2001). Tympanometric findings in cleft palate patients: Influence of age and cleft type. The Journal of Laryngology & Otology, 115(2), 91-96. https://doi.org/10.1258/0022215011906880
Ibekwe, T. S., Nwaorgu, O. G. B., & Ijaduola, T. G. A. (2010). OME and its management in Nigerian children: The role of the EarPopper®. International Journal of Pediatric Otorhinolaryngology, 74(5), 536–539.
Ibekwe, T.S., Dahilo, E.A., Folorunso, D., Uzochukwu, T., Egbe, B.I., Quadri, O.R., Fred, D., Etukumana, I., Nwankwo, B.C., & Gbujie, I.O. (2022). Update on First African Clinical Trial on EarPopper for the Treatment of Otitis Media with Effusion. Annals of African Medicine, 21(1), 65–70. https://doi.org/10.4103/aam.aam_17_21
Jain, S., & Bansal, R. (2019). The effects of age at cleft palate repair on middle ear function and hearing loss. International Journal of Pediatric Otorhinolaryngology, 123, 151-155. https://doi.org/10.1016/j.ijporl.2019.05.014
Mossey, P. A., & Modell, B. (2012). Epidemiology of oral clefts 2012: An international perspective. Frontiers of Oral Biology, 16, 1–18.
Okugbo, S. U. (2015). Otologic assessment in cleft lip and palate patients in a developing country. Nigerian Journal of Clinical Practice, 18(2), 158–163.
Olusanya, B. O. (2004). Self-reported outcomes of aural rehabilitation in a developing country. International Journal of Audiology, 43(10), 563–571.
Olusanya, B. O. (2011). Highlights of the new WHO report on newborn and infant hearing screening and implications for developing countries. International Journal of Pediatric Otorhinolaryngology, 75(6), 745–748.
Olusanya, B.O. (2008). Hospital-based universal newborn hearing screening for early detection of permanent congenital hearing loss in Lagos, Nigeria. International Journal of Pediatric Otorhinolaryngology, 72(7), 991–1001. https://doi.org/10.1016/j.ijporl.2008.03.004
Paradise, J.L., Feldman, H.M., Campbell, T.F., Dollaghan, C.A., Colborn, D.K., Bernard, B.S., Rockette, H.E. & Kurs-Lasky, M. (2001). Effect of early or delayed insertion of tympanostomy tubes for persistent otitis media on developmental outcomes at the age of three years. New England Journal of Medicine, 344(16), pp. 1179–1187.
Rosenfeld, R. M., Shin, J. J., Schwartz, S. R., Coggins, R., Gagnon, L., Hackell, J. M., ... & Corrigan, M. D. (2016). Clinical practice guideline: Otitis media with effusion (update). Otolaryngology–Head and Neck Surgery, 154(1_suppl), S1–S41.
Sheahan, P., Miller, I., Sheahan, J. N., Earley, M. J., & Blayney, A. W. (2003). Incidence and outcome of middle ear disease in cleft lip and/or cleft palate. Clinical Otolaryngology, 28(3), 220–225.
Sheahan, P., Miller, I., Sheahan, J.N., Earley, M.J. & Blayney, A.W. (2003). Hearing outcomes following cleft palate repair. Clinical Otolaryngology and Allied Sciences, 28(5), pp. 447–451.
Sheer, F. J., Swarts, J. D., Ghadiali, S. N., & Doyle, W. J. (2010). Effect of cleft palate repair on eustachian tube function: A computational modeling study. The Laryngoscope, 120(2), 265-272. https://doi.org/10.1002/lary.20677
Vanderas, A. P. (1987). Incidence of cleft lip, cleft palate, and cleft lip and palate among races: A review. Cleft Palate Journal, 24(3), 216–225.
Yanti, A., & Susanto, I. (2020). Middle ear problems in children with cleft palate: A cross-sectional study. Annals of Otology and Rhinology, 5(6), 203-208. https://doi.org/10.1177/0003489420922016
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